Jovana Jakovljević Uzelac

Jovana Jakovljević Uzelac
Biografija: Dr Jovana Jakovljević Uzelac je asistent, zaposlena od 2012. godine na Institutu za Medicinsku fiziologiju, Medicinskog fakulteta u Beogradu. Medicinski fakultet, Univerziteta u Beogradu završila je 2010. godine.  Doktorske akademske studije, modul Fiziološke nauke upisala je školske 2011/2012 god. Tema doktorske disertacije „Uticaj vitamin B6 i folne kiseline na funkcionalne, biohemijske i imunohistohemijske karakteristike kardiovaskularnog sistema pacova sa srčanom insuficijencijom izazvanom monokrotalinom” odobrena je na Veću naučnih oblasti medicinskih nauka Univerziteta u Beogradu, a za mentora je imenovan profesor dr Dragan Đurić. Jovana Jakovljević Uzelac je član Laboratorije za kardiovaskularnu fiziologiju u kojoj se sprovode istraživanja na projektu Ministarstva prosvete, nauke i tehnološkog razvoja Republike Srbije pod nazivom „Efekti homocisteina i homocisteinu-srodnih supstanci na kardiovaskularni sistem: uloga gasnih transmitera NO, H2S i CO“ čiji je rukovodilac profesor dr Dragan Đurić. Od 2014. godine angažovana je na istom projektu. Takođe, Jovana Jakovljević Uzelac je od 2011.godine angažovana i na projektu pod nazivom „ Značaj polimorfizma glutation S-transferaza u podložnosti za nastanak oboljenja“ (Projekat Ministarstva prosvete, nauke i tehnološkog razvoja Republike Srbije) čiji je rukovodilac profesor dr Tatjana Simić. Specijalizaciju iz Laboratorijske medicine upisala je 2013. god.

Oblasti užeg interesovanja: kardiovaskularna fiziologija, oksidativni stres

Učešće na stručnim simpozijumima i naučnim konferencijama:

  1. 85th EAS Congress, Czech Republic, 2017
  2. 8th International Symposium on Neurocardiology, Neurocard, Serbia, 2016
  3. Symposium on occasion of 30 years of “Blaubeuren Conferences” of the Tübingen Institute of Physiology with special  participation from Danubian countries, Inflammatory Diseases – pathophysiological, clinical and therapeutic aspects, Blaubeuren, Germany, 2014
  4. Heart failure 2012, Belgrade, Serbia, 2012

Spisak naučnih radova:

 Originalni radovi in extenso u časopisima sa JCR (journal citation reports) liste

  1. Uzelac Jakovljevic J, Stanic M, Krstic D, Colovic M, Djuric D. Effects of homocisteine and its related compounds on oxygen consumption of the rat heart tissue homogenate: the role of different gasotransmitters. Mol Cell Biochem 2017, In press doi 10.1007/s11010-017-3238-z (M23, IF=2,669)
  2. Suvakov S, Damjanovic T, Pekmezovic T, Jakovljevic J, Savic-Radojevic A, Pljesa-Ercegovac M, Radovanovic S, Simic DV, Pljesa S, Zarkovic M, Mimic-Oka J, Dimkovic N, Simic T. Associations between GSTM1*0 and GSTA1*A genotypes with the risk of cardiovascular death among hemodialyses patients. BioMed Central Nephrology 2014 ( M23, IF= 1,644)
  3. Skoric D, Joksic I, Radic T, Jakovljevic J, Ivanovski P, Simic T. Methylenetetrahydrofolate reductase and glutathione S-tranferase gene polymorphisms in secondary mixed phenotype acute leukemia: a case report. J Pediatr Hematol Oncol. 2014 ( M23, IF= 0,973)
  4. Suvakov S, Damjanovic T, Stefanovic A, Pekmezovic T, Savic-Radojevic A, Pljesa-Ercegovac M, Matic M, Djukic T, Coric V, Jakovljevic J, Ivanisevic J, Pljesa S, Jelic-Ivanovic Z, Mimic-Oka J, Dimkovic N, Simic T. Glutathione S-transferase A1, M1, P1 and T1 null or low-activity genotypes are associated with enhanced oxidative damage among haemodialysis patients. Nephrol Dial Transplant 2013;28(1):202-12 ( M21, IF= 3,371)

Izvodi u zbornicima međunarodnih naučnih skupova

  1. Djuric D, Micovic Z, Stamenković A, Jakovljević Uzelac J, Stojanović M, Sćepanović Lj, Mitrović D, Labudović Borović M, Krstić D, Colović M, Obrenović R, Hadzibegović A, Kostić S, Sobot T, Jakovljević V. Joint Meeting of National Physiological Societies ’New perspectives in physiological research-young investigator forum’, Serbia, 2017
  2. Jakovljević Uzelac J, Colović M, Krstić D, djurić M, Djurić D. The effects of nitric oxide synthase inhibition following acute administration of homocysteine on oxidative stress markers in rat plasma. 85th EAS Congress, Czech Republic, 2017
  3. Djurić D, Obrenović R, Djurić M, Stevanović A, Jakovljević J, Kostić S, Hadzibegović A, Stanojlović O. The effects of subchronic methionine load alters certain biochemical parameters, vitamin B12 level and von Willebrand factor activity in blood of male wistar rats. 31st annual convention of
    the German Atherosclerosis Society, Germany, 2017
  4. Djurić D, Colović M, Krstić D, Obrenović R, Djurić M, Stevanović M, Stamenković A, Jakovljević Uzelac J,Kostić S, Hadzibegović A.The effects of subchronic methionine overload on body weight, standard biochemical parameters, homocysteine level and onse plasma oxidative stress following acute methionine administration in male wistar rats. 8th International Symposium on Neurocardiology is a Medical, Cardiology and Neurology Symposium, Neurocard, Serbia, 2016
  5. Djurić D, Zivković V, Jeremić N, Srejović I, Djordjević D, Colović M, Stanić M, Krstić D, Djurić M, Stevanović A, Jakovljević J, Radenković M, Stanojlović O, Jakovljević V. Cardiovascular effects of homocysteine and related thiolactone metabolites: what we learnt from extensive five years lasting research? 2nd joint Meeting of Slovak and Serbian Physiological Societies ’Physiology without frontiers’, Slovakia, 2016
  6. Stanić M, Zakrzewska J, Miladinović Z, Jakovljević J, Čolović M, Krstić D, Djurić D. Effects of homocysteine isoforms on oxygen consumption of the rat heart tissue homogenate: the role of different gasotransmitters.3rd congress of Physiological Sciences of Serbia with international Participation, Serbia, 2014
  7. Veselinovic M, Jakovljevic J, Zivkovic V, Toncev S, Jakovljevic V, Djuric D. Clinical parameters of endothelial dysfunction in patients with rheumatoid arthritis: the results of an observational study. Symposium on occasion of 30 years of “Blaubeuren Conferences” of the Tübingen Institute of Physiology with special  participation from Danubian countries, Inflammatory Diseases – pathophysiological, clinical and therapeutic aspects, Blaubeuren, Germany, 2014
  8. Djuric D, Zivkovic V, Srejovic I, Joksimovic J, Selakovic D, Barudzic N, Jakovljevic J, Jakovljevic V. Effects DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: the role of different gasotransmitters. Symposium on occasion of 30 years of “Blaubeuren Conferences” of the Tübingen Institute of Physiology with special  participation from Danubian countries, Inflammatory Diseases – pathophysiological, clinical and therapeutic aspects, Blaubeuren, Germany, 2014
  9. Savic Radojevic A, Simic T, Bozic I,  Bjekic Macut J, Coric V, Djukic T, Jakovljevic J, Zarkovic M, Panidis D, Macut Dj. Effect of hyperglycemia and hyperinsulinemia on glutathione peroxidase activity in non-obese women with polycystic ovary syndrome. Inernational Symposium on Advances in PCOS, Serbia, 2012, FC2
  10. Ercegovac M, Coric V, Simic T, Jovic N, Sokic D, Jakovljevic J, Kecmanovic M, Nikolic D, Jankovic S, Savic-Radojevic A, Pljesa-Ercegovac M. Glutathione Transferase Polymorphisms in Patients with Progressive Myoclonic Epilepsy. 10th European Congress on Epileptology London, UK, 2012, P065
  11. Coric V, Pljesa Ercegovac M, Matic M, Suvakov S, Jakovljevic J, Savic Radojevic A, Djukic T, Simic T. Glutathione S‐transferase single nucleotide gene polymorphisms and susceptibility to renal cell carcinoma: Serbian case‐control study”, Proceedings for SFRR-/IUBMB Advanced School 2012, Spetses, Greece, 2012, P08
  12. Coric V, Jankovic N, Radovanovic S, Suvakov S, Јakovljevic J, Djukic T, Rakocevic I, Simic DV. GSTM1 and GSTT1-Null genotypes are associated with higher risk of chronic heart failure among hypertensive and obese Heart failure 2012, Belgrade, Serbia, 2012, Abstract 60962
  13. Pljesa-Ercegovac M, Coric V, Matic M, Suvakov S, Jakovljevic J, Djukic T, Savic-Radojevic A, Simic T. Genetic polymorphisms in glutathione S-transferases A1, M1 and T1 and risk of renal cell carcinoma: Serbian case-control study. 4th Annual Meeting on Cancer and Control of Genomic Integrity, Zandvoort, Netherlands, 2011, Abstract book, p50.
  14. Savic-Radojevic A, Djukic T, Pljesa-Ercegovac M, Matic M, Suvakov S, Coric V, Jakovljevic J, Simic T. GSTM1-null genotype is associated with higher degree of DNA damage in patients with urinary bladder carcinoma. 4th Annual Meeting on Cancer and Control of Genomic Integrity, Zandvoort, Netherlands, 2011, Abstract book, p52.
  15. Coric V, Pljesa-Ercegovac M, Matic M, Suvakov S, Jakovljevic J, Savic-Radojevic A, Djukic T, Simic T. Glutathione S-transferase A1, M1 and T1 gene polymorphism and susceptibility to renal cell carcinoma: Serbian case-control study. Society for Free Radical Research – Europe Meeting 2011, Istanbul, Turkey, 2011, Abstract book, P3-091.
  16. Suvakov S, Damjanovic T, Dimkovic N, Pljesa S, Coric V, Matic M, Jakovljevic J, Pljesa-Ercegovac M, Savic-Radojevic A,  Djukic T, Simic T. Chronic renal failure patients with Val105Val genotype exhibit enhanced oxidative stress. Society for Free Radical Research – Europe Meeting 2011, Istanbul, Turkey, 2011, Abstract book, P1-020.
  17. Jakovljevic J, Matic M, , Suvakov S, Coric V, Djukic T, Savic-Radojevic A , Pljesa-Ercegovac M, Simic T. Glutathione S-transferase A1 and P1 polymorphism and risk of smoking-related bladder cancer. Society for Free Radical Research – Europe Meeting 2011, Istanbul, Turkey, 2011, Abstract book, YIS-05.
  18. Milovanović B, Krajinović T, Milićević N, Jovanović M, Jakovljević J. The short time poincare plot and autonomic dysfunction in patients with myocardial infarction. International Symposium on Neurocardiology-Neurocard 2009, Belgrade, Serbia, 2009, Abstract book p32.
  19. Milovanovic B, Jovanovic M, Jakovljevic J. Heritability of heart rate variability and autonomic nervous system adjustment (ANSA): New approach in diagnosis and treatment of syncope. III Russian Congress, Clinical Electrocardiology, Санкт-Петербург, Russia, 2009, Abstract book p129.
  20. Luka S, Svetel M, Kostic V, Krotin M, Milovanovic A, Jovanovic M, Jakovljevic J, Kostic S. Depressed heart rate variability and sudden heart death risk in patients with Parkinson’s disease and multiple system atrophy. 12th Congress of the European Federation of Neurological Societies, Madrid, Spain, 2008, Abstract book p242.
  21. Milovanovic B, Bisenic V, Krotin M, Andrejic J, Banicevic S, Jovanovic M, Jakovljevic J, Kopanja D, Saponjski J. The short time poincare plot form and parameters of heart rate variability in early and late phase after myocardial infarction. II Russian Congress, Clinical Electrocardiology, Суздалб, Russia, 2008, Abstract book p38.
  22. Milovanovic B, Bisenic V, Banicevic S, Andrejic J, Krotin M, Kopanja D, Saponjski J, Rogozarski J, Jovanovic M, Jakovljevic J. The short time poincare plot form and cardiac death risk in patients with myocardial infarction. X International Congress, International Society for Holter and Noninvasive Electrocardiology, Zakopane Koscielisko, Poland, 2008, Abstract book p10.
  23. Jakovljevic J, Aleksic A, Vasilić Dj. Risk factors for age-related hip fracture identified in population of Serbia. 15th Annual International Ain Shams Medical Students’ Congress, Cairo, Egypt, 2007, Abstract book

Izvodi u zbornicima domaćih naučnih skupova

  1. Jakovljević J, Đukić T, Savić-Radojević A, Matić M, Plješa-Ercegovac M, Šuvakov S, Ćorić V i Simić T. Povezanost glutation s-transferaze M1*0 genotipa sa visokim stepenom oksidativnog oštećenja DNK kod bolesnika sa karcinomom mokraćne bešike. Prvi kongres „Mitohondrije i slobodni radikali u biomedicini“, Beograd, 2011, Knjiga sažetaka p61
  2. Matić M, Pekmezović T, Đukić T, Mimic-Oka J, Dragičević D, Krivić B, Šuvakov S, Savić-Radojević A, Plješa-Ercegovac M, Ćorić V, Jakovljević J i Simić T. Glutation transferaze kao biomarkeri rizika za nastanak karcinoma mokraćne bešike. Prvi kongres „Mitohondrije i slobodni radikali u biomedicini“, Beograd, 2011, Knjiga sažetaka p20.
  3. Šuvakov S, Damjanović T, Dimković N, Plješa S, Ćorić V, Matić M, Jakovljević J, Plješa-Ercegovac M, Savić-Radojević A, Đukić T i Simić T. Povećan oksidativni stress kod bolesnika obolelih od hronične bubrežne insuficijencije sa GSTP1 Val105Val genotipom. Prvi kongres „Mitohondrije i slobodni radikali u biomedicini“, Beograd, 2011, Knjiga sažetaka p36.
  4. Ćorić V, Plješa-Ercegovac M, Matić M, Šuvakov S, Jakovljević J, Đukić T, Savić-Radojević A i Simić T. Uloga polimorfizma glutation s-transferaza A1, M1 i T1 kod pacijenata sa karcinomom bubrežnog parenhima. Prvi kongres „Mitohondrije i slobodni radikali u biomedicini“, Beograd, 2011, Knjiga sažetaka p82.